Your age, weight, and diet are some of the factors your healthcare provider will take into account when determining an appropriate dosage of Pancreaze. This medicine comes as a delayed-release capsule that is taken with each meal. For young children or those who cannot swallow the capsules, the contents can be poured onto applesauce or other slightly acidic food.
The dose of Pancreaze® (pancrelipase) your healthcare provider recommends will vary, depending on the following factors:
- Your age and weight
- Your diet (especially how much fat you eat)
- How you respond to the medication.
As is always the case, do not adjust your dose unless your healthcare provider specifically tells you to do so.
It should be noted that pancrelipase products, including Pancreaze, are typically dosed based on lipase content, although they contain lipases, amylases, and proteases.
The standard adult dosage for Pancreaze varies, depending on the severity of pancreatic enzyme deficiency symptoms, weight, and previous response to similar medications. A reasonable starting dose is 500 units (based on lipase content) per kg of body weight per meal (about 227 units of lipase per lb per meal).
Your healthcare provider can increase your dose as needed. Typically, half the normal mealtime dosage is used for snacks. Alternatively, your healthcare provider can also recommend a dosing strategy based on how much fat you eat instead of how much you weigh.