For infants up to 12 months of age, the standard dose for any pancrelipase product is 2,000 to 4,000 units of lipase for each 120 mL of formula or breast milk ingested, before each bottle or each breastfeeding session. Note that the smallest strength of Pancreaze contains 4,200 units of lipase. As a result, this product may not be appropriate for many infants. Other pancrelipase products, which come in lower strengths, might be more appropriate.
For children 12 months to 4 years of age, the standard starting dosage is usually 1000 units (based on lipase content) per kg of body weight per meal (about 455 units per lb per meal).
For children age 4 and older, the starting dosage is usually 500 units (based on lipase content) per kg of body weight per meal (about 228 units of lipase per lb per meal), with half the normal mealtime dosage used for snacks.
In all cases, your child's healthcare provider may adjust the amount as necessary.
Some considerations to keep in mind during treatment with Pancreaze include the following:
- This medication comes in the form of a delayed-release capsule. It is usually taken by mouth with each meal, or before each feeding for an infant.
- For infants, the capsules should be opened, and the contents administered directly into the mouth or with a small amount of applesauce or commercially-prepared pear or banana baby food. Follow immediately with formula or breastfeeding.
- For small children, or other individuals unable to swallow capsules, open the capsules and sprinkle the contents on a cold, slightly acidic food, such as applesauce. Swallow (without chewing) the applesauce completely and immediately. Follow with water or juice.
- Do not crush or chew the capsules, as this will destroy the delayed-release properties of the capsules and may cause mouth irritation.
- For the medication to work properly, it must be taken as prescribed. Your symptoms will return if you stop taking this medication.
- If you are unsure about anything related to your dosage, please talk with your healthcare provider, nurse, or pharmacist.