Pancreaze and Breastfeeding
No studies have been done to determine if Pancreaze (pancrelipase) passes through breast milk. However, because this medicine is approved for use in infants, it is believed to be safe for use while nursing. In many cases, the benefits to the breastfeeding woman using Pancreaze would exceed the potential risks to a nursing infant.
Pancreaze® (pancrelipase) is a prescription medication approved for the treatment of pancreatic enzyme deficiencies (such as the type of deficiency that occurs with cystic fibrosis), known medically as exocrine pancreatic insufficiency (EPI). It is unknown if Pancreaze passes through breast milk in humans.
Pancreaze has not been studied in any breastfeeding women or animals, so it is unknown if it passes through breast milk. However, keep in mind that the drug is approved for use in babies, which means it has been shown to be safe in infants. This suggests, but does not prove, that it would probably be safe for use during breastfeeding.
Breastfeeding is a time of increased nutritional need for mothers, and it would not be a good time to leave a pancreatic digestive enzyme deficiency untreated, due to the risk for malnutrition. In many (if not most) cases, the benefits to the breastfeeding woman exceed the potential risks to the breastfed child.
You should discuss breastfeeding and Pancreaze use with your healthcare provider. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision that is right for you.