Cystic Fibrosis Home > Pancreaze

If you have a deficiency of pancreatic enzymes, your healthcare provider may prescribe Pancreaze. This drug is approved to increase pancreatic enzymes in people who have cystic fibrosis or certain other conditions. It comes as a delayed-release capsule that is taken with each meal. Clinical studies suggest that people tolerate this medication well and that side effects are uncommon.

What Is Pancreaze?

Pancreaze® (pancrelipase) is a prescription medication used to replace pancreatic enzymes (digestive enzymes secreted by the pancreas) in people with a deficiency of these enzymes. It is approved for use in people with cystic fibrosis or other conditions that cause pancreatic digestive enzyme deficiencies. Such deficiencies are often referred to as "exocrine pancreatic insufficiency."
Pancreaze is exactly the same as Pancrease MT, an older drug that is no longer available in the United States. Prior to 2010, Pancrease MT was available but was an unapproved drug, as is common with older medications that were available before the United States Food and Drug Administration started regulating drugs. When it was officially approved in 2010, the name was changed to Pancreaze, although the product remains the same.
(Click Pancreaze Uses for more information.)

Who Makes This Medication?

Pancreaze is made by Nordmark Arzneimittel GmbH & Co. KG (a German manufacturer) for Janssen Pharmaceuticals, Inc.

How Does Pancreaze Work?

Pancreaze contains a mixture of different pancreatic enzymes taken from the pancreatic glands of pigs. Specifically, it contains lipases, proteases, and amylases. Lipases help to digest fats, proteases help to digest proteins, and amylases help to digest starches.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation

Topics & Medications


Related Channels

eMedTV Links
Copyright © 2006-2020 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.