Cystic Fibrosis Home > Kalydeco Uses
How Does It Work?In people with certain mutations of the CFTR (cystic fibrosis transmembrane conductance regulator) protein, the CFTR ion channels have a much lower likelihood of opening, compared to normal CFTR channels.
Kalydeco is a CFTR protein potentiator. This means that it helps to increase the probability that the CFTR channel opens to allow flow of chloride ions across cell membranes. This helps to correct the main problem rather than just addressing symptoms in people with this type of cystic fibrosis.