Creon Side Effects
Taking Creon may cause some people to develop coughing, dizziness, or vomiting. Extensive clinical trials showed that other common side effects of Creon include abdominal (stomach) pain and common cold symptoms. There are also some potentially serious problems that can occur, such as high uric acid levels and a dangerous condition called fibrosing colonopathy.
Just like any medicine, Creon® (pancrelipase) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in many cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Creon. Your healthcare provider can discuss a more complete list with you.)
Creon has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking the drug were carefully documented and compared to those that occurred in a group of people taking a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
In clinical studies, the most common Creon side effects included:
- High blood sugar levels (hyperglycemia) -- in up to 8 percent of people
- Vomiting -- up to 6 percent
- Dizziness -- up to 4 percent
- Cough -- up to 4 percent
- Low blood sugar levels (hypoglycemia) -- up to 4 percent
- Abdominal (stomach) pain -- up to 4 percent
- Abnormal stool -- up to 4 percent
- Flatulence -- up to 4 percent
- Frequent bowel movements -- up to 4 percent
- Common cold symptoms -- up to 4 percent.